Given the potential of these 2 markers to unveil important aspects of stroke pathophysiology, the paucity of available data in the literature and the likely availability of information to physicians at the bedside in a very near future, we decided in the present study to investigate the simultaneous assessment of GFAP and UCH-L1 in patients presenting with stroke-like symptoms and their relation to initial stroke severity and patient characteristics. The gene discussed is UCHL1; the disease is Stroke.