We screened a panel of AKT inhibitors using FLT3 inhibitors AC220 [8] and TCS359 [9] as positive controls against FLT3-ITD-positive (MOLM13, MOLM14 and MV4-11) and FLT3 wt (U937, HL-60, PF382, SKM-1, NB4 and OCI-AML3) AML cell lines. This evidence concerns the gene FLT3 and acute myeloid leukemia.