The results showed that PD-1+ and γδ T lymphocytes were associated with poor OS respectively (HR = 1.60; 95%CI, 1.15–2.23 and HR = 3.34; 95%CI, 1.21–9.23), while CD3+ lymphocytes indicated better OS (HR = 0.31; 95%CI, 0.14–0.70).CD4+ lymphocytes were not prognostic markers in breast cancer (S4B Fig). The gene discussed is CD4; the disease is breast carcinoma.