CD4 and infection: Of note, the number of IFN-γ-producing CD4+ and CD8+ T-cells was detected only in the Lb infection; however, on the evolution of the infection, the number of IFN-γ-producing CD4+ T-cells decreased, while the number of IFN-γ-producing CD8+ T-cells increased (Figures 5(e) and 5(f)).