COL4A2 and intracerebral hemorrhage: In addition, 2 of the SNPs, rs9515201[COL4A2] and rs2984613[PMF1-BGLAP], are also associated with intracerebral hemorrhage.10,22 This serves to emphasize that shared pathophysiological processes seem to underlie many of the clinical manifestations of cerebral SVD and suggests that a coordinated attempt to identify cerebral SVD associations will likely be fruitful.