BIRC5 and breast cancer: Our past miRNA studies of BC cells showed that clustered miRNAs (including miR-1/133a (targeting TAGLN2), miR-23b/27b/24-1 (targeting EGFR, MET, and FOXM1), and miR-195/497 (targeting BIRC5 and WNT7A)) act as tumor-suppressive miRNAs through their regulation of several oncogenic genes and pathways [10, 17–19].