GSN and carcinoma: Furthermore, when compared with the two mutants, the specificity of the effect of E7 wt on the induction of cell migration (Figure 5B) and invasion (Figure 5C) strengthens once again the hypothesis that the physical interaction between E7 and GSN could induce a cascade of events in cytoskeletal network, increasing the overall cell motility and migration of C-33A carcinoma cells.