In recent years, tradition prudent Chinese diet pattern has been affected by western diet pattern, more intake of sugar sweet drinks increased the sugar intake in Chinese diet, excessive intake of sweet drinks can increase energy intake, insulin resistance, oxidative stress and inflammation, accelerating LTL shortening, and regular consumption of sugar-sweetened beverage might influence metabolic disease development through accelerated cell aging [32, 33]. The gene discussed is INS; the disease is metabolic disease.