RELN and schizophrenia: For example, a rare missense variant (chr7:103194134 T > C, p.Tyr1981Cys) was detected in Bulgarian trio de novo exome sequencing SCZ sample24; some rare non-synonymous and disruptive mutations of RELN gene were found in Swedish SCZ patients19 (See Schizophrenia Exome Sequencing Genebook).