INS and type 2 diabetes mellitus: Type 2 diabetes can often be controlledinitially with diet and exercise and with antidiabetic drugs such asmetformin (which suppresses glucose production by the liver) andsulfonylureas (which stimulate the secretion of insulin by the pancreas).However, as the disease progresses, the pancreatic beta cells becomeimpaired, and many patients eventually need insulin injections to preventhyperglycemia.