In addition, PTRF co-expresses with KRT1, CCT5 co-expresses with MHI1; GOT1 co-expresses with MHI1; and MHI1 co-expresses with LDHB; indicating not only an interaction between LDHB, GOT1 and MDH1, but also a possible association between them and the leiomyoma. The gene discussed is CAVIN1; the disease is leiomyoma.