A significant increase (p < 0.01) in MDA (2.18 ± 0.55 versus 1.45 ± 0.40) and LDL carbonyl protein (27.15 ± 5.82 versus 10.85 ± 3.21) and a significant decrease (p < 0.01) in the activity of antioxidant enzyme, SOD (3.61 ± 2.73 versus 7.27 ± 2.87), used as a prognostic tool in assessing the risk of cardiovascular disease have been observed in normolipidemic CVD menopausal women as compared to non-CVD ones. Here, SOD1 is linked to cardiovascular disorder.