IL7R and systemic lupus erythematosus: Indeed, several lines of study have recently suggested that an elevated level of plasma sIL-7R in SLE patients was correlated with or predicted the occurrence of an SLE nephritis flare, indicating that the serum sIL-7R concentration may be a potential biomarker with high sensitivity and specificity for diagnosis of SLE patients with LN [25, 26, 35].