While various reports suggest that ICK is a regulator of cilia length [5, 6, 8], we did not observe dramatic differences in the length of cilia expressing mutant ICK nor in those cilia occurring on the apical surface of cells derived from an ECO patient (Additional file 6: Figure S4 and Additional file 7: Figure S5). Here, CILK1 is linked to endocrine-cerebro-osteodysplasia syndrome.