INS and type 2 diabetes mellitus: Type 2 diabetes (T2D) is a chronic metabolic disorder considered to be the fifth cause of death in the world after infectious diseases, cardiovascular diseases, cancer and trauma is accompanied with insulin resistance of the whole body and myocardial cells.1 This type of diabetes is the most common type of mellitus diabetes and is a serious threat for the health of mankind in the 21st century and due to its rapid expansion, has attracted much attention in the last two decades.2 Type 2 diabetic people are threaten by cardiovascular diseases and cardiac failure.