CD4 and tuberculosis: The frequency of D0 CD4+ T cells (estimated OR 0.95 per 1 unit increase, P=0.027, FDR=0.198) and the magnitude of D0 BCG-specific T cells secreting IFN-γ (estimated OR 0.46 per 1 log10 unit increase, P=0.03, FDR=0.198) were associated with reduced risk of TB disease (Fig. 2a,c).