The p24 concentration in MDM supernatant was indeed reduced of about 40–50 % for both viruses produced in shUNG2- or in shUNG2/shRPA32-tranduced cells 8 days after infection, showing that simultaneous depletion of UNG2 and RPA32 had no additional or synergistic effects compared to viruses produced in UNG2-depleted cells. This evidence concerns the gene UNG and infection.