The strongest evidence of shared association was seen at 6p24 (locus no. 1 of table 2), where both CAD and migraine showed genome-wide significant signals within the PHACTR1 gene (CAD: rs4714955, p = 9.8 × 10−11; migraine: rs9349379, p = 5.9 × 10−9). Here, PHACTR1 is linked to migraine disorder.