Parental consanguinity has been found to be significantly associated with familial forms of DORV, but only a couple of genes have been associated with the pathophysiology of the disease like CFC1 (cripto, FRL‐1, cryptic family 1), and ZFPM2 (zinc finger protein, multitype 2) (Goldmuntz et al. The gene discussed is ZFPM2; the disease is double outlet right ventricle.