IL1A and infection: In our work, analysis of the production of the proinflammatory cytokines IFNγ, IL-1α, and GM-CSF demonstrated significant activation of their synthesis in mouse granuloma cells after 20 days, one month, and two months following infection with the BCG vaccine in vivo and at different times of ex vivo culture, while mouse bone marrow cells and peritoneal macrophages infected with the BCG vaccine in vitro were not observed to induce their synthesis.