For example, elevated FA levels have been found in brains of patients suffering from neurodegenerative diseases like Alzheimer's disease (AD) or multiple sclerosis (MS) [22–24], where FA is known to cross-link proteins like tau (in AD) or myelin basic protein (MBP, in MS), which in turn results in the proteins losing their normal function and elicits an immune response that is characteristic of the diseases [20, 24]. Here, MAPT is linked to early-onset autosomal dominant Alzheimer disease.