Except for the direction of the pain trajectory, all other features of the head pain in this woman are consistent with those of the previously reported LH in some patients, including the line-shaped pain area innervated by different nerves and the migrainous features of pulsating pain character, triggering or facilitating factor of anxiety, accompaniments of dizziness, head heaviness, and photophobia and phonophobia (Wang et al. 2014a). This evidence concerns the gene PLOD1 and Photophobia.