AKT1 and chronic obstructive pulmonary disease: Interestingly, Tannerstedt et al. showed a difference in anabolic response between type‐I and type‐II muscle fibres, with increased AKT phosphorylation and downstream pathway activation in the type‐II fibres.69 In contrast, in COPD, the respiratory muscle with a shift towards more type‐I fibres displayed a larger AKT activation and downstream signalling than the limb muscles with a shift towards more type‐II fibres.