With the goal of reaching maternal glycaemia in a normal range, so to avoid deleterious consequences of hyperglycaemia in the growing fetus, patients diagnosed with GDM are subjected to controlled diet (plus a suggested routine of exercise) or treated with insulin [i.e., insulin therapy; Verier-Mine, 2010; American Diabetes Association (ADA), 2015; Sobrevia et al., 2015]. This evidence concerns the gene INS and gestational diabetes.