Whereas, in normal pregnancies maternal hypercholesterolaemia associates with lower expression of LDL receptor (LDLR) in homogenized placenta (Ethier-Chiasson et al., 2007; Desoye et al., 2011), expression of the HDL scavenger receptor class B type I (SR-BI) and LDLR is increased in GDM compared with normal pregnancies (Dubé et al., 2013). This evidence concerns the gene LDLR and Hypercholesterolemia.