MAPT and Alzheimer disease: Being thus far the only compound to be able to visualize tau (and possibly different isoforms) in AD, but also in PSP and CBD (Maruyama et al., 2013), 2-((1E, 3E)-4-(6-([11C]methylamino)pyridin-3-yl)buta-1,3-dienyl)benzo[d]thiazol-6-ol ([11C]PBB3) received a lot of interest (Figure 5).