Only one MAO binding PET tracer has been elevated on AD patients thus far: [11C]methyl[(2R)-1-phenylpropan-2-yl][(1,1-2H2)prop-2-yn-1-yl]amine ([11C]DED), an irreversible MAO-B inhibitor (Hirvonen et al., 2009; Carter et al., 2012; Choo et al., 2014). This evidence concerns the gene MAOB and Alzheimer disease.