TERT and urinary bladder cancer: Two TERT promoter mutations (1 295 228 C>T and 1 295 250 C>T, referred to as124C>T and146C>T, respectively, in the following text), particularly the 124C>T mutation, have been identified in bladder cancer and glioblastoma[9], suggesting a role for TERT promoter mutations inhuman tumorigenesis.