Moreover, the IL8 expression of in vitro M cells was upregulated 14.929 fold after WT S. Typhimurium WT infection (S3 Table); however, this upregulation was increased approximately 1.5 times after S. Typhimurium ΔspeG infection (22.356-fold change, S5 Table). The gene discussed is CXCL8; the disease is infection.