MMP-2 is up-regulated following different irradiation protocols in various tumor types such as glioblastoma (Kargiotis et al., 2008), pancreatic (Qian et al., 2002), lung (Chetty et al., 2009) and colorectal cancers (Speake et al., 2005), leading to increased tumor invasion. This evidence concerns the gene MMP2 and neoplasm.