Four missense mutations (p.Arg398Gln, p.Tyr796His, p.Met896Ile, and p.Arg928Cys) in KCNT1 gene were reported to be associated with ADNFLE cases showing comorbidities of intellectual disability and psychiatric features (Heron et al., 2012). The gene discussed is KCNT1; the disease is autosomal dominant nocturnal frontal lobe epilepsy.