Blocking the renin-angiotensin-aldosterone system in ST-elevation myocardial infarction (STEMI) patients prevents heart failure and recurrent thrombosis in particular by the use of angiotensin-converting-enzyme (ACE) inhibitors if there are no contraindications to their use [1, 2]. The gene discussed is REN; the disease is ST Elevation Myocardial Infarction.