ASPG and acute myeloid leukemia: The fact that asparaginase and vincristine are minimally myelosuppressive is important for patients such as Jehovah’s Witnesses that do not accept blood product transfusion; as it is well known that the use of conventional chemotherapy for remission induction in AML results in life-threatening anemia and thrombocytopenia, requiring blood product transfusions with an average of 10.8 and 8.5 units of red blood cell and platelet transfusions, respectively [31].