FBXO21 and infection: In the presence of MG132 that blocks the degradation of Fbxo21, we found that VSV infection could not decrease Fbxo21 while HSV-1 infection could induce the expression of Fbxo21 protein 12 hr after infection (Figure 6—figure supplement 1C), confirming that VSV and HSV-1 may differentially regulate the transcription of Fbxo21.