GNAL and Onset: Cellular models suggest that the Tor1A gene mutation induces inhibition of the cyclic adenosine monophosphate response to an adenylyl cyclase 5 agonist.42 DYT25 causes adult‐onset generalized dystonia attributed to loss of function in the GNAL gene.43, 44 This gene codes for guanine nucleotide‐binding protein, alpha‐activating activity polypeptide, olfactory type [Ga(olf)], which is abundant in the striatum45).