CCL2 and neoplasm: Consistent with similar CCL2 levels in CRCLMs, there was no significant difference in the density of CD68-positive tumor-associated macrophages in CRCLMs from patients treated with placebo (median 272 cells [IQR 222-375] per hpf; n=24) compared with EPA (median 281 cells [IQR 188-362] per hpf; n=28) (Figure 1E).