TIMP3 and non-small cell lung carcinoma: We found that high KDM1A or low TIMP3 expression was significantly associated with poor prognosis of NSCLC patients, irrespective of grade and histology, with logrank (Mantel-Cox) P values of 0.032 for KDM1A and 0.00014 for TIMP3 (Figure 8A and 8B).