CD276 and nonpapillary renal cell carcinoma: In the present study, the level of B7-H3 expression was higher in the tumor cells, tumor vasculatures, and stroma of the ccRCC samples than in normal renal specimens, which was consistent with previous studies, providing a theoretical basis for 131I-labeled targeted radiotherapy for RCC using B7-H3 monoclonal antibody (4H7) as a carrier.