This functional class includes Cd2, Cd274, Cd300a, Cd33, Cd3g, Cd40, Cd84, Clec10a, Clec4b1, Clec4d, Ifnar2, Il10ra, Il1r2, Ly9, Osmr, Slamf9, Tnfrsf11a, Tnfrsf11b, Tnfrsf4 and Vcam1, in addition to chemokine receptors Ccr5 and Cxcr3. Overexpression of these functional classes is commonly observed in infection-related gene expression studies, indicating their fundamental functions in host responses against diverse pathogens. The gene discussed is VCAM1; the disease is infection.