By assessing the relative mRNA expression levels of B7-H4 in tumor tissues and the paired adjacent normal tissues with real-time PCR assay, researchers found that B7-H4 mRNA expression was confirmed in all of tumor specimens and B7-H4 mRNA expression level was higher in tumor tissues than adjacent normal tissues (P<0.01) [21, 27]. Here, VTCN1 is linked to neoplasm.