SERPINF1 and cancer: To provide additional in vivo support for our hypothesis that PEDF mitigates fibrosis, tissue sections from the same patient cohort used previously (Figure 1, N=66) were stained via H&E and Mason's trichrome, and fibrosis scored from 0-3+, also by two blinded investigators (representative images Figure 7a) As expected, the mean trichrome score was significantly higher in cancer specimens compared to adjacent normal tissue (Figure 7b).