Nonetheless, alteration of genes attributed to the initial autophagosomes formation, e.g. Beclin1 (Atg6), Atg5, Atg12, UVRAG (UV radiation resistance-associated gene) and MAP1LC3 (Microtubule-associated proteins 1A/1B light chain 3), has been linked to tumor development [6, 7]. The gene discussed is BECN1; the disease is neoplasm.