Six viral proteins (Helicase2, RR2, NRK, Mabr112, Mabr129 (AC53) and ChtB1) were only identified in ODV virions from H. armigera and 7 proteins [V-CATH, Mabr38, Mabr58, Mabr64, IAP2, IAP3 and Mabr135 (AC43)] were only identified in that from S. exigua. LC-MS/MS analysis identified a total of 39 viral proteins in BV, 22 of which were common to BVs produced in either H. armigera or S. exigua. Most of the common proteins are essential for nucleocapsid assembly and transport (Fig 1A and S3 Table). The gene discussed is RRM2; the disease is bacterial vaginosis.