moDC expressed similar amounts of cGAS compared with moMΦ (as shown by western blot and qPCR), and produced higher or similar levels of cGAMP compared with GM-CSF MΦ (as shown by mass spectrometry analysis) upon HCMV or MVA infection; however, moDC produced significantly less IFN-I than moMΦ. The gene discussed is CGAS; the disease is infection.