c.235delC was recently reported to manifest a dynamic range of SNHL and a slightly milder audiologic phenotype compared with other GJB2 variants in Koreans.34 Detection of mutations in MYO15A and TMC1 in group I are relatively common in East Asian populations, including Koreans,2,35–38 indicating that application of panel sequencing covering the genes prioritized based on the ethnicity-specific prevalence would be effective for identifying GJB2 single heterozygotes with severe to profound SNHL in Koreans. Here, GJB2 is linked to sensorineural hearing loss disorder.