When we excluded two cases (Group II) with the GJB2 mutation contributing to SNHL possibly through digenic inheritance, we still observed a slightly higher rate of GJB2 single heterozygotes (Group I + III) than in the normal controls (4.38% vs. 2.58%, P = 0.20), although the difference was not statistically significant. Here, GJB2 is linked to sensorineural hearing loss disorder.