According to the TCGA database (cBioportal for cancer genomics; http://www.cbioportal.org), these genes all appear to be altered to different extents in cutaneous and desmoplastic melanoma (278 cases and 20 cases, respectively), whereas NBN appears to be altered in 21% of uveal melanoma cases (80 cases) (Supplementary Figure 3). Here, NBN is linked to desmoplastic melanoma.