On the other hand, Ly6Chigh monocytes displayed high expression of MIF receptors CXCR4 (Figure S4: (A)-(B)) and CD74 (Figure S4: (C)-(D)), compared to Ly6Clow monocytes at 5 days after infection or resident Mφs (F4/80high) from uninfected mice, which could explain the selective role of MIF in inducing activation and differentiation of Ly6Chigh monocytes into TipDCs. Here, MIF is linked to infection.