IL6 and bacterial meningitis: There was a significant difference between meningeal inflammation of infected WT and TNFR1−/− or TNFR1-IL-6−/− mice: 12.4 ± 0.7 for WT, 7.3 ± 0.7 for TNFR1−/− mice (p = 0.0003 compared to WT), 12.1 ± 0.9 for IL-6−/−-deficient mice, and 8.3 ± 0.8 (p = 0.0019; n = 10 each group; Mann-Whitney U test) reflecting a lower attraction of neutrophil granulocytes to the meninges in these mice in bacterial meningitis.