Our previous studies have shown that miR-193a-3p is involved in multi-drug resistance in both hepatocellular carcinoma [25] and bladder cancer [26, 27] via the repression of different target genes, including SRSF2, PLAU, HIC2 and LOXL4 [26, 27]. The gene discussed is HIC2; the disease is urinary bladder carcinoma.