NKAPD1 and neoplasm: The α-Hed-CS-NP surface was then modified with monoclonal antibody CD147 and formedα-Hed-CS-CD147-NPs with sizes ranging from 50 to 300 nm, which showed a higher cellular uptake and intracellular accumulation in human liver cancer cell lines HepG2 and SMMC-7721 than free α-Hed and α-Hed-CS-NPs, and also had higher targeting antitumor efficacy at the tumor sites in nude mice.