Taken in sum with the results of the present study, HU induces γ-globin through numerous networks comprising BCL11A, KLF-1, TAL-1 and MYB. The data of this study also demonstrated an association between miR-26b and γ-globin expression, which has previously been shown both at basal and MTD in HU-treated SCD patients [44]. The gene discussed is MYB; the disease is Schnyder corneal dystrophy.