Overexpression, activating mutations and activating gene fusions in FGFR3 have also been identified in multiple myeloma, glioblastoma multiforme, bladder, cervical, gastric, colorectal, head and neck squamous, and germ cell-derived cancers (Dieci et al., 2013; Ornitz and Itoh, 2015; Turner and Grose, 2010). Here, FGFR3 is linked to glioblastoma.