Pathology scores of control mice not injected with D11 antibody, or experimental mice injected with D11 antibody, were not different (mean pathology score: without antibody 2.5±1.4, with antibody injection 2.5±1.4), indicating that once tumors were established, inhibition of FGFR3 was not sufficient to accelerate tumor regression of these FGF9–FGFR3-independent tumors (data not shown). This evidence concerns the gene FGFR3 and neoplasm.